Friday, September 14, 2018 by Michelle Simmons
Sheng Jiang San, a traditional Chinese multi-herb tonic, has been used to treat seasonal influenza but there has been no evidence that supports its anti-influenza efficacy. A study published in the journal BMC Complementary and Alternative Medicine recently confirmed that Sheng Jiang San can help treat influenza.
- Researchers from China investigated the effects of Sheng Jiang San against influenza in cells and in mice.
- They tested the effects of Sheng Jiang San against different influenza virus strains on cells, while they employed H1N1 influenza virus on mice.
- Then, they orally gave mice one gram per kilogram (g/kg) of Sheng Jiang San every day for a period of seven days.
- They monitored the mice for 14 days and measured their survival rate, body weight changes, lung index, lung viral load, histopathologic changes, and immune regulation.
- They also analyzed how Sheng Jiang San worked against influenza virus through a series of biological assays.
- Results revealed that Sheng Jiang San exhibited inhibitory effects on multiple influenza strains on cells in a dose-dependent manner.
- The administration of Sheng Jiang San on mice also protected them from H1N1 infection.
- Compared with untreated mice, mice treated with Sheng Jiang San experienced significant reductions in their lung index and lung viral load. This indicates that the treatment might work on the virus directly and could reduce lung injury caused by the influenza virus.
- It could improve the survival rate of mice and bring back their normal weight.
- It also demonstrated anti-influenza activity by inhibiting neuraminidase activity and regulating cytokine expression.
These findings indicated that Sheng Jiang San can inhibit influenza virus strains and act against the influenza virus.
Read the full text of the study at this link.
To read more stories on traditional Chinese medicine, visit ChineseMedicine.news today.
Zhang T, Xiao M, Wong C-K, Chris Mok K-P, Zhao X, Ti H, Shaw P-C. SHENG JIANG SAN, A TRADITIONAL MULTI-HERB FORMULATION, EXERTS ANTI-INFLUENZA EFFECTS IN VITRO AND IN VIVO VIA NEURAMINIDASE INHIBITION AND IMMUNE REGULATION. BMC Complementary and Alternative Medicine. 8 May 2018; 18(150). DOI: 10.1186/s12906-018-2216-7